BECLIN1 Is Essential for Podocyte Secretory Pathways Mediating VEGF Secretion and Podocyte-Endothelial Crosstalk

BECLIN1 Is Essential for Podocyte Secretory Pathways Mediating VEGF Secretion and Podocyte-Endothelial Crosstalk

Vascular endothelial growth factor A (VEGFA) secretion from podocytes is crucial for maintaining endothelial integrity within the glomerular filtration barrier. However, until now, the molecular mechanisms underlying podocyte secretory function remained unclear. Through podocyte-specific deletion of...

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Bibliographic Details
Main Authors: Tillmann Bork, Wei Liang, Oliver Kretz, Simon Lagies, Kosuke Yamahara, Camila Hernando-Erhard, Martin Helmstädter, Christoph Schell, Bernd Kammerer, Tobias B. Huber
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:International Journal of Molecular Sciences
Subjects:
podocyte
BECLIN1
autophagy
secretory pathway
Golgi network
VEGF
Online Access:https://www.mdpi.com/1422-0067/23/7/3825

Internet

https://www.mdpi.com/1422-0067/23/7/3825

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