Co-transplantation of Mesenchymal Stromal Cells and Induced Pluripotent Stem Cell-Derived Cardiomyocytes Improves Cardiac Function After Myocardial Damage

Co-transplantation of Mesenchymal Stromal Cells and Induced Pluripotent Stem Cell-Derived Cardiomyocytes Improves Cardiac Function After Myocardial Damage

Induced pluripotent stem cell-derived cardiomyocytes (iPS-CMs) represent an attractive resource for cardiac regeneration. However, survival and functional integration of transplanted iPS-CM is poor and remains a major challenge for the development of effective therapies. We hypothesized that paracri...

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Bibliographic Details
Main Authors: Klaus Neef, Florian Drey, Vera Lepperhof, Thorsten Wahlers, Jürgen Hescheler, Yeong-Hoon Choi, Tomo Šarić
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
myocardial infarction
induced pluripotent stem cells
cardiomyocytes
mesenchymal stem cells
imaging
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2021.794690/full

Internet

https://www.frontiersin.org/articles/10.3389/fcvm.2021.794690/full

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