Aconitum carmichaelii triggers neurotoxicity and Parkinson‐like symptoms through initiation of ROS‐mitochondrial apoptosis and the Nox5/DJ‐1 signaling pathway

Aconitum carmichaelii triggers neurotoxicity and Parkinson‐like symptoms through initiation of ROS‐mitochondrial apoptosis and the Nox5/DJ‐1 signaling pathway

Abstract Background Aconitum carmichaelii, the mother root of Aconitum, has a long‐applied history for treating many diseases in China. Increased use of it has prompted significant concerns regarding its extensive cardiotoxicity and neurotoxicity. The molecular mechanisms underlying A. carmichaelii‐...

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Bibliographic Details
Main Authors: Meijun Pang, Xin Song, Yaodong Miao, Yiwen Wang, Chang Zhou, Zihan Geng, Jiayin Du, Bernard Moussian, Yanfang Su, Xiuyun Liu, Dong Ming
Format: Article
Language:English
Published: Wiley 2023-06-01
Series:BMEMat
Subjects:
Aconitum Carmichaelii
apoptosis
neurotoxicity
oxidative stress
zebrafish
Online Access:https://doi.org/10.1002/bmm2.12019

Internet

https://doi.org/10.1002/bmm2.12019

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