Two immune-enhanced molecular subtypes differ in inflammation, checkpoint signaling and outcome of advanced head and neck squamous cell carcinoma

Two immune-enhanced molecular subtypes differ in inflammation, checkpoint signaling and outcome of advanced head and neck squamous cell carcinoma

The immune environment of primary tumor is associated with the clinical response and benefit of immunotherapy. This study aims to investigate the intratumoral immune profile and its clinical relevance in advanced head and neck squamous cell carcinoma (HNSCC). Gene expression profiles of 401 HNSCCs a...

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Bibliographic Details
Main Authors: Bangrong Cao, Qifeng Wang, Huan Zhang, Guiquan Zhu, Jinyi Lang
Format: Article
Language:English
Published: Taylor & Francis Group 2018-02-01
Series:OncoImmunology
Subjects:
hnscc
molecular subtype
inflammation
immune checkpoint pathway
hpv
Online Access:http://dx.doi.org/10.1080/2162402X.2017.1392427

Internet

http://dx.doi.org/10.1080/2162402X.2017.1392427

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