Immunogenicity of SARS-CoV-2 Trimeric Spike Protein Associated to Poly(I:C) Plus Alum

Immunogenicity of SARS-CoV-2 Trimeric Spike Protein Associated to Poly(I:C) Plus Alum

The SARS-CoV-2 pandemic has had a social and economic impact worldwide, and vaccination is an efficient strategy for diminishing those damages. New adjuvant formulations are required for the high vaccine demands, especially adjuvant formulations that induce a Th1 phenotype. Herein we assess a vaccin...

Full description

Bibliographic Details
Main Authors: Júlio Souza dos-Santos, Luan Firmino-Cruz, Alessandra Marcia da Fonseca-Martins, Diogo Oliveira-Maciel, Gustavo Guadagnini Perez, Victor A. Roncaglia-Pereira, Carlos H. Dumard, Francisca H. Guedes-da-Silva, Ana C. Vicente Santos, Monique dos Santos Leandro, Jesuino Rafael Machado Ferreira, Kamila Guimarães-Pinto, Luciana Conde, Danielle A. S. Rodrigues, Marcus Vinicius de Mattos Silva, Renata G. F. Alvim, Tulio M. Lima, Federico F. Marsili, Daniel P. B. Abreu, Orlando C. Ferreira Jr., Ronaldo da Silva Mohana Borges, Amilcar Tanuri, Thiago Moreno L. Souza, Bartira Rossi-Bergmann, André M. Vale, Jerson Lima Silva, Andréa Cheble de Oliveira, Alessandra D’Almeida Filardy, Andre M. O. Gomes, Herbert Leonel de Matos Guedes
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Immunology
Subjects:
poly (I:C)
alum
adjuvants
intradermal route
spike protein
vaccine
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.884760/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.884760/full

Similar Items