Single-cell profiling reveals immune disturbances landscape and HLA-F-mediated immune tolerance at the maternal-fetal interface in preeclampsia

Single-cell profiling reveals immune disturbances landscape and HLA-F-mediated immune tolerance at the maternal-fetal interface in preeclampsia

BackgroundPreeclampsia is a pregnancy-specific disorder that always causes maternal and fetal serious adverse outcome. Disturbances in maternal immune tolerance to embryo at the maternal-fetal interface (MFI) may be associated with preeclampsia onset. Recent studies have revealed the reduced express...

Full description

Bibliographic Details
Main Authors: Fangyuan Luo, Fulin Liu, Yingzhe Guo, Wenming Xu, Yilin Li, Jun Yi, Thierry Fournier, Séverine Degrelle, Hedia Zitouni, Isabelle Hernandez, Xinghui Liu, Yu Huang, Jun Yue
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Immunology
Subjects:
preeclampsia
placental decidua
single-cell RNA sequencing
immune tolerance
maternal-fetal interface
human leucocyte antigen
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1234577/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1234577/full

Similar Items