Ferroptotic alveolar epithelial type II cells drive TH2 and TH17 mixed asthma triggered by birch pollen allergen Bet v 1

Abstract Asthma is a common allergic disease characterized by airway hypersensitivity and airway remodeling. Ferroptosis is a regulated death marked by iron accumulation and lipid peroxidation. Several environmental pollutants and allergens have been shown to cause ferroptosis in epithelial cells, b...

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Bibliographic Details
Main Authors: Linyi Ma, Ying He, Huancheng Xie, Jing Wang, Jiaqian Chen, Shijie Song, Le Zhang, Linmei Li, He Lai, Yongping Liu, Huifang Chen, Xueyan Zhang, Xueting Liu, Zehong Zou, Qingling Zhang, Jie Yan, Ailin Tao
Format: Article
Language:English
Published: Nature Publishing Group 2024-02-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-024-01861-3