Out of plane distortions of the heme b of Escherichia coli succinate dehydrogenase.

The role of the heme b in Escherichia coli succinate dehydrogenase is highly ambiguous and its role in catalysis is questionable. To examine whether heme reduction is an essential step of the catalytic mechanism, we generated a series of site-directed mutations around the heme binding pocket, creati...

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Bibliographic Details
Main Authors: Quang M Tran, Carmen Fong, Richard A Rothery, Elena Maklashina, Gary Cecchini, Joel H Weiner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3290573?pdf=render