Enhanced Signal-to-Noise and Fast Calibration of Optical Tweezers Using Single Trapping Events

The trap stiffness us the key property in using optical tweezers as a force transducer. Force reconstruction via maximum-likelihood-estimator analysis (FORMA) determines the optical trap stiffness based on estimation of the particle velocity from statistical trajectories. Using a modification of thi...

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Bibliographic Details
Main Authors: Alexander B. Stilgoe, Declan J. Armstrong, Halina Rubinsztein-Dunlop
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Micromachines
Subjects:
Online Access:https://www.mdpi.com/2072-666X/12/5/570