Generation of HLA-Universal iPSC-Derived Megakaryocytes and Platelets for Survival Under Refractoriness Conditions

Generation of HLA-Universal iPSC-Derived Megakaryocytes and Platelets for Survival Under Refractoriness Conditions

Abstract Platelet (PLT) transfusion is indispensable to maintain homeostasis in thrombocytopenic patients. However, PLT transfusion refractoriness is a common life-threatening condition observed in multitransfused patients. The most frequent immune cause for PLT transfusion refractoriness is the pre...

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Bibliographic Details
Main Authors: Ann-Kathrin Börger, Dorothee Eicke, Christina Wolf, Christiane Gras, Susanne Aufderbeck, Kai Schulze, Lena Engels, Britta Eiz-Vesper, Axel Schambach, Carlos A Guzman, Nico Lachmann, Thomas Moritz, Ulrich Martin, Rainer Blasczyk, Constança Figueiredo
Format: Article
Language:English
Published: BMC 2016-05-01
Series:Molecular Medicine
Online Access:http://link.springer.com/article/10.2119/molmed.2015.00235

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http://link.springer.com/article/10.2119/molmed.2015.00235

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