Formulation and evaluation of a smart drug delivery system of 5-fluorouracil for pH-sensitive chemotherapy

The conventional chemotherapeutic drugs have many side effects due to their non-selective tissue distribution, reduced drug concentration of the drug at the tumor site, and the drug resistance. To overcome these problems the chemotherapeutic agent should selectively accumulate the tumor site and sta...

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Bibliographic Details
Main Authors: Shamla Cheralayikkal, K. Manoj, K.P. Safna Hussan
Format: Article
Language:English
Published: Elsevier 2022-07-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844022012142