Selective Targeting and Eradication of Various Human Non-Small Cell Lung Cancer Cell Lines Using Self-Assembled Aptamer-Decorated Nanoparticles

Selective Targeting and Eradication of Various Human Non-Small Cell Lung Cancer Cell Lines Using Self-Assembled Aptamer-Decorated Nanoparticles

The leading cause of cancer mortality remains lung cancer (LC), of which non-small cell lung cancer (NSCLC) is the predominant type. Chemotherapy achieves only low response rates while inflicting serious untoward toxicity. Herein, we studied the binding and internalization of S15-aptamer (S15-APT)-d...

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Bibliographic Details
Main Authors: Daniel Barak, Shira Engelberg, Yehuda G. Assaraf, Yoav D. Livney
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Pharmaceutics
Subjects:
lung cancer
anticancer drugs
paclitaxel
targeted delivery
aptamers
nanoparticles
Online Access:https://www.mdpi.com/1999-4923/14/8/1650

Internet

https://www.mdpi.com/1999-4923/14/8/1650

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