Network pharmacology and experimental verification-based strategy for exploring the mechanisms of luteolin in the treatment of osteosarcoma

Network pharmacology and experimental verification-based strategy for exploring the mechanisms of luteolin in the treatment of osteosarcoma

Abstract Background Luteolin is an active ingredient in various traditional Chinese medicines for the treatment of multiple tumors. However, the mechanisms of its inhibitory effect on osteosarcoma proliferation and metastasis remain unclear. Purpose To elucidate the anti-osteosarcoma mechanisms of l...

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Bibliographic Details
Main Authors: Renxuan Huang, Mingxian Xu, Weitang Guo, Mingzhe Cheng, Rui Dong, Jian Tu, Shao Xu, Changye Zou
Format: Article
Language:English
Published: BMC 2023-09-01
Series:Cancer Cell International
Subjects:
Luteolin
Network pharmacology
Osteosarcoma
Molecular docking
scRNA-seq
Orthotopic mouse model
Online Access:https://doi.org/10.1186/s12935-023-03046-x

Internet

https://doi.org/10.1186/s12935-023-03046-x

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