TFAP2C promotes stemness and chemotherapeutic resistance in colorectal cancer via inactivating hippo signaling pathway

TFAP2C promotes stemness and chemotherapeutic resistance in colorectal cancer via inactivating hippo signaling pathway

Abstract Background Aberrant expression of transcription Factor AP-2 Gamma (TFAP2C) has been reported to be implicated in malignant process of many cancers. The purpose of this study is to investigate the clinical significance and biological roles of TFAP2C in colorectal cancer (CRC). Methods TFAP2C...

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Bibliographic Details
Main Authors: Xu Wang, Di Sun, Jiandong Tai, Si Chen, Miao Yu, Dong Ren, Lei Wang
Format: Article
Language:English
Published: BMC 2018-02-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
TFAP2C
Chemotherapeutic resistance
Cancer stem cells
Hippo signaling and colorectal cancer
Online Access:http://link.springer.com/article/10.1186/s13046-018-0683-9

Internet

http://link.springer.com/article/10.1186/s13046-018-0683-9

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