MiR-217 Regulates SIRT1 Expression and Promotes Inflammatory and Apoptotic Responses in Osteoarthritis

MiR-217 Regulates SIRT1 Expression and Promotes Inflammatory and Apoptotic Responses in Osteoarthritis

Previous studies have reported miR-217 uregulation in age-related pathologies. We investigated the impact of miR-217-5p on sirtuin 1 (SIRT1) regulation in human osteoarthritic (OA) chondrocytes. MiR-217 target enrichment analyses were performed using three public databases, Gene Ontology and Kyoto E...

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Bibliographic Details
Main Authors: Aliki-Alexandra Papageorgiou, Athanasios Roussos, Ioanna Papathanasiou, Charalampos Balis, Theophilos Karachalios, Sokratis E. Varitimidis, Konstantinos N. Malizos, Aspasia Tsezou
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Genes
Subjects:
miR-217
SIRT1
osteoarthritis
inflammation
apoptosis
Online Access:https://www.mdpi.com/2073-4425/14/12/2155

Internet

https://www.mdpi.com/2073-4425/14/12/2155

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