Circadian rhythm disruption modulates enteric neural precursor cells differentiation leading to gastrointestinal motility dysfunction via the NR1D1/NF-κB axis

Circadian rhythm disruption modulates enteric neural precursor cells differentiation leading to gastrointestinal motility dysfunction via the NR1D1/NF-κB axis

Abstract Objectives Circadian rhythm disruption (CRD) is implicated with numerous gastrointestinal motility diseases, with the enteric nervous system (ENS) taking main responsibility for the coordination of gastrointestinal motility. The purpose of this study is to explore the role of circadian rhyt...

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Bibliographic Details
Main Authors: Yurui Zhang, Shizhao Xu, Mengke Fan, Hailing Yao, Chen Jiang, Qi He, Huiying Shi, Rong Lin
Format: Article
Language:English
Published: BMC 2024-10-01
Series:Journal of Translational Medicine
Subjects:
Circadian rhythm
NF-κB signaling
Enteric nervous system
Enteric neural precursor cells
Gastrointestinal motility
Online Access:https://doi.org/10.1186/s12967-024-05766-8

Internet

https://doi.org/10.1186/s12967-024-05766-8

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