EGFR-targeted fluorescence molecular imaging for intraoperative margin assessment in oral cancer patients: a phase II trial

EGFR-targeted fluorescence molecular imaging for intraoperative margin assessment in oral cancer patients: a phase II trial

Abstract Inadequate surgical margins occur frequently in oral squamous cell carcinoma surgery. Fluorescence molecular imaging (FMI) has been explored for intraoperative margin assessment, but data are limited to phase-I studies. In this single-arm phase-II study (NCT03134846), our primary endpoints...

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Bibliographic Details
Main Authors: Jaron G. de Wit, Jasper Vonk, Floris J. Voskuil, Sebastiaan A. H. J. de Visscher, Kees-Pieter Schepman, Wouter T. R. Hooghiemstra, Matthijs D. Linssen, Sjoerd G. Elias, Gyorgy B. Halmos, Boudewijn E. C. Plaat, Jan J. Doff, Eben L. Rosenthal, Dominic Robinson, Bert van der Vegt, Wouter B. Nagengast, Gooitzen M. van Dam, Max J. H. Witjes
Format: Article
Language:English
Published: Nature Portfolio 2023-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-40324-8

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https://doi.org/10.1038/s41467-023-40324-8

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