Base excision repair and double strand break repair cooperate to modulate the formation of unrepaired double strand breaks in mouse brain
Abstract We lack the fundamental information needed to understand how DNA damage in the brain is generated and how it is controlled over a lifetime in the absence of replication check points. To address these questions, here, we integrate cell-type and region-specific features of DNA repair activity...
| Hauptverfasser: | , , , , , , |
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| Format: | Artikel |
| Sprache: | English |
| Veröffentlicht: |
Nature Portfolio
2024-09-01
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| Schriftenreihe: | Nature Communications |
| Online Zugang: | https://doi.org/10.1038/s41467-024-51906-5 |