Current challenges for HER2 testing in diagnostic pathology: state of the art and controversial issues

HER2 overexpression and anti-HER2 agents represent probably the best story of success of individualized therapy in breast cancer. Due to the important therapeutic implications, the issue under the spotlight has been, since ever, the correct identification of true HER2 positivity on tissue specimens....

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Bibliographic Details
Main Authors: Anna eSapino, Margherita eGoia, Daniele eRecupero, Caterina eMarchio
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-05-01
Series:Frontiers in Oncology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2013.00129/full