Current challenges for HER2 testing in diagnostic pathology: state of the art and controversial issues
HER2 overexpression and anti-HER2 agents represent probably the best story of success of individualized therapy in breast cancer. Due to the important therapeutic implications, the issue under the spotlight has been, since ever, the correct identification of true HER2 positivity on tissue specimens....
Main Authors: | Anna eSapino, Margherita eGoia, Daniele eRecupero, Caterina eMarchio |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2013-05-01
|
Series: | Frontiers in Oncology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fonc.2013.00129/full |
Similar Items
-
HER2 amplification level by in situ hybridization predicts survival outcome in advanced HER2-positive breast cancer treated with pertuzumab, trastuzumab, and docetaxel regardless of HER2 IHC results
by: Jeongmin Seo, et al.
Published: (2023-12-01) -
HER2 status in breast cancer: changes in guidelines and complicating factors for interpretation
by: Soomin Ahn, et al.
Published: (2020-01-01) -
HER2 Low Breast Cancer: A New Subtype or a Trojan for Cytotoxic Drug Delivery?
by: Marina Popović, et al.
Published: (2023-05-01) -
HER2 amplification by next-generation sequencing to identify HER2-positive invasive breast cancer with negative HER2 immunohistochemistry
by: Laura Morsberger, et al.
Published: (2022-11-01) -
Targeting HER2 expression in cancer: New drugs and new indications
by: Semir Vranić, et al.
Published: (2021-02-01)