Amelioration of ligamentum flavum hypertrophy using umbilical cord mesenchymal stromal cell-derived extracellular vesicles

Amelioration of ligamentum flavum hypertrophy using umbilical cord mesenchymal stromal cell-derived extracellular vesicles

Ligamentum flavum (LF) hypertrophy (LFH) has been recognised as one of the key contributors to lumbar spinal stenosis. Currently, no effective methods are available to ameliorate this hypertrophy. In this study, human umbilical cord mesenchymal stromal cell-derived extracellular vesicles (hUCMSC-EVs...

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Bibliographic Details
Main Authors: Cheng Ma, Xin Qi, Yi-Fan Wei, Zhi Li, He-Long Zhang, He Li, Feng-Lei Yu, Ya-Nan Pu, Yong-Can Huang, Yong-Xin Ren
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2023-01-01
Series:Bioactive Materials
Subjects:
Ligamentum flavum hypertrophy
Fibrosis
Umbilical cord mesenchymal stromal cells
Extracellular vesicle
miR-146a-5p
miR-221-3p
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X2200158X

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http://www.sciencedirect.com/science/article/pii/S2452199X2200158X

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