Improved Precision-Cut Liver Slice Cultures for Testing Drug-Induced Liver Fibrosis

Improved Precision-Cut Liver Slice Cultures for Testing Drug-Induced Liver Fibrosis

In vitro models of human liver disease often fail to mimic the complex 3D structures and cellular organizations found in vivo. Precision cut liver slices (PCLS) retain the complex physiological architecture of the native liver and therefore could be an exceptional in vitro liver model. However, the...

Full description

Bibliographic Details
Main Authors: Liza Dewyse, Vincent De Smet, Stefaan Verhulst, Nathalie Eysackers, Rastislav Kunda, Nouredin Messaoudi, Hendrik Reynaert, Leo A. van Grunsven
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Medicine
Subjects:
PCLS
DILI
hepatic stellate
VPA
human
mouse
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2022.862185/full

Internet

https://www.frontiersin.org/articles/10.3389/fmed.2022.862185/full

Similar Items