Production of transgenic first filial puppies expressing mutated human amyloid precursor protein gene

Production of transgenic first filial puppies expressing mutated human amyloid precursor protein gene

Propagation of transgenic animals by germline transmission using assisted reproductive technologies such as in vitro fertilization (IVF) is the most efficient way to produce transgenic colonies for biomedical research. The objective of this study was to generate transgenic puppies from a founder dog...

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Bibliographic Details
Main Authors: Mohammad Shamim Hossein, Young-Bum Son, Yeon Woo Jeong, Yeon Ik Jeong, Mi Na Kang, Eun Ji Choi, Kang Bae Park, Yu Ra Bae, Dae Young Kim, Woo Suk Hwang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Veterinary Science
Subjects:
transgenic dogs
mhAPP gene
germline transmission
Percoll
in vitro fertilization
Online Access:https://www.frontiersin.org/articles/10.3389/fvets.2023.1227202/full

Internet

https://www.frontiersin.org/articles/10.3389/fvets.2023.1227202/full

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