Genetic Variants in the Activation of the Brown-Like Adipocyte Pathway and the Risk for Severe Obesity

Genetic Variants in the Activation of the Brown-Like Adipocyte Pathway and the Risk for Severe Obesity

Background: Regular physical activity has an important role in energy expenditure and combats the development of obesity. During exercise, PPARGC1A is overexpressed, stimulating an increase of the expression of FNDC5. This protein is cleaved to release the hormone irisin, which activates a browning...

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Bibliographic Details
Main Authors: Ana Carolina Proença  da Fonseca, Guilherme Proença  da Fonseca, Bruna Marchesini, Danielle Dutra Voigt, Mario Campos Junior, Verônica Marques Zembrzuski, João Regis Ivar Carneiro, José Firmino Nogueira Neto, Pedro Hernan Cabello, Giselda Maria Kalil Cabello
Format: Article
Language:English
Published: Karger Publishers 2020-04-01
Series:Obesity Facts
Subjects:
polymorphism
irisin
severe obesity
ucp1
ppargc1a
Online Access:https://www.karger.com/Article/FullText/505666

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https://www.karger.com/Article/FullText/505666

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