Epithelial-mesenchymal transition sensitizes breast cancer cells to cell death via the fungus-derived sesterterpenoid ophiobolin A

Epithelial-mesenchymal transition sensitizes breast cancer cells to cell death via the fungus-derived sesterterpenoid ophiobolin A

Abstract The epithelial–mesenchymal transition (EMT) imparts properties of cancer stem-like cells, including resistance to frequently used chemotherapies, necessitating the identification of molecules that induce cell death specifically in stem-like cells with EMT properties. Herein, we demonstrate...

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Bibliographic Details
Main Authors: Keighley N. Reisenauer, Yongfeng Tao, Provas Das, Shuxuan Song, Haleigh Svatek, Saawan D. Patel, Sheridan Mikhail, Alec Ingros, Peter Sheesley, Marco Masi, Angela Boari, Antonio Evidente, Alexander Kornienko, Daniel Romo, Joseph Taube
Format: Article
Language:English
Published: Nature Portfolio 2021-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-89923-9

Internet

https://doi.org/10.1038/s41598-021-89923-9

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