Targeting the CD24-Siglec10 Axis: A Potential Strategy for Cancer Immunotherapy
CD24, also known as heat-stable protein, is a highly glycosylated glycosylphosphatidylinositol junction membrane protein. CD24 specifically binds sialic-acid-binding Ig-like lectin 10 (Siglec10) on macrophages and serves as a “don’t eat me” signal, thus blocking the phagocytosis of tumor cells by ma...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Compuscript Ltd
2024-02-01
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| Series: | BIO Integration |
| Subjects: | |
| Online Access: | https://www.scienceopen.com/hosted-document?doi=10.15212/bioi-2023-0022 |