Prognostic value of prelymphodepletion absolute lymphocyte counts in relapsed/refractory diffuse large B-cell lymphoma patients treated with chimeric antigen receptor T cells

Prognostic value of prelymphodepletion absolute lymphocyte counts in relapsed/refractory diffuse large B-cell lymphoma patients treated with chimeric antigen receptor T cells

IntroductionChimeric antigen receptor (CAR) T cell therapy has achieved unprecedented efficacy recently. However, the factors related to responses and durable remission are elusive. This study was to investigate the impact of pre-lymphodepletion (pre-LD) absolute lymphocyte count (ALC) on CAR T cell...

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Bibliographic Details
Main Authors: Yanyan Lu, Hong Zhu, Yang Liu, Ying Wang, Yinxiang Sun, Hai Cheng, Zhiling Yan, Jiang Cao, Wei Sang, Feng Zhu, Depeng Li, Haiying Sun, Junnian Zheng, Kailin Xu, Zhenyu Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Immunology
Subjects:
chimeric antigen receptor T cell
diffuse large B-cell lymphoma
prelymphodepletion absolute
prognostic value
survival time
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1155216/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2023.1155216/full

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