A case report: cccDNA and pgRNA remain positive in liver tissue in a chronic hepatitis B patient with functional cure

Hepatitis B surface antigen (HBsAg) seroclearance is recommended as the ideal endpoint for nucleos(t)ide analog (NA) treatments. Functional cure of chronic hepatitis B (CHB) is defined as having undetectable serum hepatitis B virus (HBV) deoxyribonucleic acid and serum HBsAg. We report a functional...

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Bibliographic Details
Main Authors: Wenxiong Xu, Qiumin Luo, Yeqiong Zhang, Chan Xie, Liang Peng
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-10-01
Series:Frontiers in Medicine
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2024.1427043/full