Computer assisted detection of axonal bouton structural plasticity in in vivo time-lapse images

Computer assisted detection of axonal bouton structural plasticity in in vivo time-lapse images

The ability to measure minute structural changes in neural circuits is essential for long-term in vivo imaging studies. Here, we propose a methodology for detection and measurement of structural changes in axonal boutons imaged with time-lapse two-photon laser scanning microscopy (2PLSM). Correlativ...

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Bibliographic Details
Main Authors: Rohan Gala, Daniel Lebrecht, Daniela A Sahlender, Anne Jorstad, Graham Knott, Anthony Holtmaat, Armen Stepanyants
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-10-01
Series:eLife
Subjects:
bouton detection
bouton volume
structural plasticity
time-lapse imaging
synaptic strength
CLEM
Online Access:https://elifesciences.org/articles/29315

Internet

https://elifesciences.org/articles/29315

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