Comparison of intravenous sedation using midazolam versus dexmedetomidine in elderly patients with dementia: a randomized cross-over trial

Abstract Differences between the effects of intravenous sedation with midazolam (MID) and dexmedetomidine (DEX) on the cerebral function of elderly patients with severe dementia are unclear. This study aimed to compare the effects of intravenous sedation with MID or DEX on parameters such as brain w...

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Bibliographic Details
Main Authors: Yoshinari Morimoto, Megumi Hayashi, Yuki Yao, Hitomi Nishizaki, Hidechika Ishii, Lou Mikuzuki, Kouji Hara
Format: Article
Language:English
Published: Nature Portfolio 2022-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-10167-2