Macrophage LRP1 Promotes Diet-Induced Hepatic Inflammation and Metabolic Dysfunction by Modulating Wnt Signaling

Hepatic inflammation is associated with the development of insulin resistance, which can perpetuate the disease state and may increase the risk of metabolic syndrome and diabetes. Despite recent advances, mechanisms linking hepatic inflammation and insulin resistance are still unclear. The low-densi...

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Bibliographic Details
Main Authors: Dianaly T. Au, Mary Migliorini, Dudley K. Strickland, Selen C. Muratoglu
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2018/7902841