Barcoding Genetically Distinct Plasmodium falciparum Strains for Comparative Assessment of Fitness and Antimalarial Drug Resistance

Barcoding Genetically Distinct Plasmodium falciparum Strains for Comparative Assessment of Fitness and Antimalarial Drug Resistance

ABSTRACT The repeated emergence of antimalarial drug resistance in Plasmodium falciparum, including to the current frontline antimalarial artemisinin, is a perennial problem for malaria control. Next-generation sequencing has greatly accelerated the identification of polymorphisms in resistance-asso...

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Bibliographic Details
Main Authors: Manuela Carrasquilla, Ndey F. Drammeh, Mukul Rawat, Theo Sanderson, Zenon Zenonos, Julian C. Rayner, Marcus C. S. Lee
Format: Article
Language:English
Published: American Society for Microbiology 2022-10-01
Series:mBio
Subjects:
apicomplexan parasites
drug resistance
fitness
malaria
Online Access:https://journals.asm.org/doi/10.1128/mbio.00937-22

Internet

https://journals.asm.org/doi/10.1128/mbio.00937-22

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