The structural basis of gas-responsive transcription by the human nuclear hormone receptor REV-ERBbeta.
Heme is a ligand for the human nuclear receptors (NR) REV-ERBalpha and REV-ERBbeta, which are transcriptional repressors that play important roles in circadian rhythm, lipid and glucose metabolism, and diseases such as diabetes, atherosclerosis, inflammation, and cancer. Here we show that transcript...
Váldodahkkit: | , , , , , , , , , , , , |
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Materiálatiipa: | Artihkal |
Giella: | English |
Almmustuhtton: |
Public Library of Science (PLoS)
2009-02-01
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Ráidu: | PLoS Biology |
Liŋkkat: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19243223/?tool=EBI |