IgSF11 deficiency alleviates osteoarthritis in mice by suppressing early subchondral bone changes

Abstract Osteoarthritis (OA) is a degenerative joint disease. While it is classically characterized by articular cartilage destruction, OA affects all tissues in the joints and is thus also accompanied by local inflammation, subchondral bone changes, and persistent pain. However, our understanding o...

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Bibliographic Details
Main Authors: Gyeong Min Kim, Jihee Kim, June-Yong Lee, Min-Chan Park, Soo Young Lee
Format: Article
Language:English
Published: Nature Publishing Group 2023-12-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-023-01126-6