IgSF11 deficiency alleviates osteoarthritis in mice by suppressing early subchondral bone changes
Abstract Osteoarthritis (OA) is a degenerative joint disease. While it is classically characterized by articular cartilage destruction, OA affects all tissues in the joints and is thus also accompanied by local inflammation, subchondral bone changes, and persistent pain. However, our understanding o...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2023-12-01
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Series: | Experimental and Molecular Medicine |
Online Access: | https://doi.org/10.1038/s12276-023-01126-6 |