Polycaprolactone-collagen nanofibers loaded with dexamethasone and simvastatin as an osteoinductive and immunocompatible scaffold for bone regeneration applications

Physiological inflammation has been shown to promote bone regeneration; however, prolonged inflammation impedes the osteogenesis and bone repair process. To overcome the latter we aimed to develop a dual drug delivering nanofibrous scaffold to promote osteogenic differentiation of mesenchymal stroma...

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Bibliographic Details
Main Authors: Hilal Ahmad Rather, Johnna Francis Varghese, Bindiya Dhimmar, Umesh C.S. Yadav, Rajesh Vasita
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Biomaterials and Biosystems
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666534422000265