Multi-arm multi-stage trials can improve the efficiency of finding effective treatments for stroke: a case study

Abstract Background Many recent Stroke trials fail to show a beneficial effect of the intervention late in the development. Currently a large number of new treatment options are being developed. Multi-arm multi-stage (MAMS) designs offer one potential strategy to avoid lengthy studies of treatments...

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Bibliographic Details
Main Authors: Thomas Jaki, James M. S. Wason
Format: Article
Language:English
Published: BMC 2018-11-01
Series:BMC Cardiovascular Disorders
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12872-018-0956-4