S14G-humanin confers cardioprotective effects against chronic adrenergic and pressure overload-induced heart failure in mice

S14G-humanin (HNG), an analog of the mitochondria-derived peptide humanin, has demonstrated protective effects against various cardiovascular diseases. However, the specific pharmacological effects of HNG in heart failure (HF) have not been previously reported. Therefore, in this study, we aimed to...

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Bibliographic Details
Main Authors: Qi Zhao, Ming-Ming Cai, Dan Li, Bin-Yi Zhao, Shuang-Shan Zhou, Zhen-Ru Wu, Yu-Jun Shi, Li Su
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023091004