Prunella vulgaris polysaccharide inhibits herpes simplex virus infection by blocking TLR-mediated NF-κB activation

Prunella vulgaris polysaccharide inhibits herpes simplex virus infection by blocking TLR-mediated NF-κB activation

Abstract Background Prunella vulgaris polysaccharide extracted by hot water and 30% ethanol precipitation (PVE30) was reported to possess potent antiviral effects against herpes simplex virus (HSV) infection. However, its anti-HSV mechanism has not yet been fully elucidated. Purpose This study aimed...

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Bibliographic Details
Main Authors: Xuanlei Zhong, Yibo Zhang, Man Yuan, Lin Xu, Xiaomei Luo, Rong Wu, Zhichao Xi, Yang Li, Hongxi Xu
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Chinese Medicine
Subjects:
Herpes simplex virus
Prunella vulgaris polysaccharide
TLR/NF-κB signalling pathway
Necroptosis
Online Access:https://doi.org/10.1186/s13020-023-00865-y

Internet

https://doi.org/10.1186/s13020-023-00865-y

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