BACH1 regulates the differentiation of vascular smooth muscle cells from human embryonic stem cells via CARM1-mediated methylation of H3R17

BACH1 regulates the differentiation of vascular smooth muscle cells from human embryonic stem cells via CARM1-mediated methylation of H3R17

Summary: The role of BACH1 in the process of vascular smooth muscle cell (VSMC) differentiation from human embryonic stem cells (hESCs) remains unknown. Here, we find that the loss of BACH1 in hESCs attenuates the expression of VSMC marker genes, whereas overexpression of BACH1 after mesoderm induct...

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Bibliographic Details
Main Authors: Yunquan He, Jieyu Guo, Yueyang Yu, Jiayu Jin, Qingjun Jiang, Qinhan Li, Siyu Ma, Qi Pan, Jiayi Lin, Nan Jiang, Jinghua Ma, Yongbo Li, Yannan Hou, Xiuling Zhi, Lindi Jiang, Lefeng Qu, Elena Osto, Xinhong Wang, Xiangxiang Wei, Dan Meng
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Cell Reports
Subjects:
CP: Molecular biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723014808

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http://www.sciencedirect.com/science/article/pii/S2211124723014808

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