Evaluation of AXIN1 and AXIN2 as targets of tankyrase inhibition in hepatocellular carcinoma cell lines
Abstract AXIN1 mutations are observed in 8–10% of hepatocellular carcinomas (HCCs) and originally were considered to support tumor growth by aberrantly enhancing β-catenin signaling. This view has however been challenged by reports showing neither a clear nuclear β-catenin accumulation nor clearly e...
| Váldodahkkit: | , , , , , , , , , |
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| Materiálatiipa: | Artihkal |
| Giella: | English |
| Almmustuhtton: |
Nature Portfolio
2021-04-01
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| Ráidu: | Scientific Reports |
| Liŋkkat: | https://doi.org/10.1038/s41598-021-87091-4 |