Development of Resistance to Clarithromycin and Amoxicillin-Clavulanic Acid in Lactiplantibacillus plantarum In Vitro Is Followed by Genomic Rearrangements and Evolution of Virulence

ABSTRACT Ensuring the safety of the use of probiotics is a top priority. Obviously, in addition to studying the beneficial properties of lactic acid bacteria, considerable attention should be directed to assessing the virulence of microorganisms as well as investigating the possibility of its evolut...

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Main Authors: V. V. Kostenko, A. A. Mouzykantov, N. B. Baranova, E. A. Boulygina, M. I. Markelova, D. R. Khusnutdinova, M. V. Trushin, O. A. Chernova, V. M. Chernov
Format: Article
Language:English
Published: American Society for Microbiology 2022-06-01
Series:Microbiology Spectrum
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/spectrum.02360-21