Epithelial Cell Rests of Malassez Provide a Favorable Microenvironment for Ameliorating the Impaired Osteogenic Potential of Human Periodontal Ligament Stem Cells

Epithelial Cell Rests of Malassez Provide a Favorable Microenvironment for Ameliorating the Impaired Osteogenic Potential of Human Periodontal Ligament Stem Cells

Human periodontal ligament stromal/stem cells (PDLSCs) are ideal candidates for periodontal regeneration and are of significant importance in clinical practice. However, PDLSCs derived from diseased microenvironments exert impaired behavior, which leads to the failure of periodontal regeneration. Th...

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Bibliographic Details
Main Authors: Yanjiao Li, Anqi Liu, Liqiang Zhang, Zhiwei Wang, Nana Hui, Qiming Zhai, Lishu Zhang, Zuolin Jin, Fang Jin
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Physiology
Subjects:
periodontal ligament stromal/stem cells
epithelial cell rests of Malassez
osteogenesis
co-culture
Wnt pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.735234/full

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https://www.frontiersin.org/articles/10.3389/fphys.2021.735234/full

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