CMHX008, a novel peroxisome proliferator-activated receptor γ partial agonist, enhances insulin sensitivity in vitro and in vivo.

The peroxisome proliferator-activated receptor γ (PPARγ) plays an important role in adipocyte differentiation and insulin sensitivity. Its ligand rosiglitazone has anti-diabetic effect but is frequently accompanied with some severe unwanted effects. The aim of the current study was to compare the an...

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Bibliographic Details
Main Authors: Yue Ming, Xiangnan Hu, Ying Song, Zhiguo Liu, Jibin Li, Rufei Gao, Yuyao Zhang, Hu Mei, Tingwang Guo, Ling Xiao, Bochu Wang, Chaodong Wu, Xiaoqiu Xiao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4087031?pdf=render