Viral DNA Binding Protein SUMOylation Promotes PML Nuclear Body Localization Next to Viral Replication Centers

Viral DNA Binding Protein SUMOylation Promotes PML Nuclear Body Localization Next to Viral Replication Centers

ABSTRACT Human adenoviruses (HAdVs) have developed mechanisms to manipulate cellular antiviral measures to ensure proper DNA replication, with detailed processes far from being understood. Host cells repress incoming viral genomes through a network of transcriptional regulators that normally control...

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Bibliographic Details
Main Authors: Miona Stubbe, Julia Mai, Christina Paulus, Hans Christian Stubbe, Julia Berscheminski, Maryam Karimi, Samuel Hofmann, Elisabeth Weber, Kamyar Hadian, Ron Hay, Peter Groitl, Michael Nevels, Thomas Dobner, Sabrina Schreiner
Format: Article
Language:English
Published: American Society for Microbiology 2020-04-01
Series:mBio
Subjects:
DNA binding protein
E2A/DBP
HAdV
human adenovirus
PML-NB
SUMO
Online Access:https://journals.asm.org/doi/10.1128/mBio.00049-20

Internet

https://journals.asm.org/doi/10.1128/mBio.00049-20

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