Pyrrolidine Derivatives as New Inhibitors of ?-Mannosidases and Growth Inhibitors of Human Cancer Cells
New pyrrolidine-3,4-diol derivatives were prepared from D-(?)- and L-(+)-phenylglycinol and tested for their ability to inhibit 25 commercial glycosidases. The influence of the substitution of the lateral side chain and of the pyrrolidine ring on the enzyme inhibition was evaluated. (2R,3R...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | deu |
| Published: |
Swiss Chemical Society
2006-04-01
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| Series: | CHIMIA |
| Subjects: | |
| Online Access: | https://chimia.ch/chimia/article/view/4144 |