Integrated transcriptional‐phenotypic analysis captures systemic immunomodulation following antiangiogenic therapy in renal cell carcinoma patients

Integrated transcriptional‐phenotypic analysis captures systemic immunomodulation following antiangiogenic therapy in renal cell carcinoma patients

Abstract Background The combination of immune checkpoint blockade (ICB) with standard therapies is becoming a common approach for overcoming resistance to cancer immunotherapy in most human malignancies including metastatic renal cell carcinoma (mRCC). In this regard, insights into the immunomodulat...

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Bibliographic Details
Main Authors: Darawan Rinchai, Elena Verzoni, Veronica Huber, Agata Cova, Paola Squarcina, Loris De Cecco, Filippo deBraud, Raffaele Ratta, Matteo Dugo, Luca Lalli, Viviana Vallacchi, Monica Rodolfo, Jessica Roelands, Chiara Castelli, Damien Chaussabel, Giuseppe Procopio, Davide Bedognetti, Licia Rivoltini
Format: Article
Language:English
Published: Wiley 2021-06-01
Series:Clinical and Translational Medicine
Subjects:
antiangiogenics
bioinformatics
blood transcriptomic profile
cancer biomarkers
immunomonitoring
immunosuppression
Online Access:https://doi.org/10.1002/ctm2.434

Internet

https://doi.org/10.1002/ctm2.434

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