Regulation of a vascular plexus by gata4 is mediated in zebrafish through the chemokine sdf1a.

Regulation of a vascular plexus by gata4 is mediated in zebrafish through the chemokine sdf1a.

Using the zebrafish model we describe a previously unrecognized requirement for the transcription factor gata4 controlling embryonic angiogenesis. The development of a vascular plexus in the embryonic tail, the caudal hematopoietic tissue (CHT), fails in embryos depleted of gata4. Rather than formin...

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Bibliographic Details
Main Authors: Ingrid Torregroza, Audrey Holtzinger, Karen Mendelson, Ting-Chun Liu, Timothy Hla, Todd Evans
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3463525?pdf=render

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http://europepmc.org/articles/PMC3463525?pdf=render

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