Simultaneous Determination of Five Iridoids of <i>Picrorhiza scrophulariiflora</i> in Rat Plasma Using UHPLC-ESI-MS/MS

Simultaneous Determination of Five Iridoids of <i>Picrorhiza scrophulariiflora</i> in Rat Plasma Using UHPLC-ESI-MS/MS

In this study, we developed an ultra-performance liquid chromatography-electrospray tandem quadrupole mass spectrometry (UHPLC-ESI-MS/MS) method to simultaneously determine Picroside-I, Picroside-II, Picroside-III, minecoside, and sweroside in rat plasma. The chromatographic column was an ACQUITY UH...

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Bibliographic Details
Main Authors: Zhibin Wang, Xuepeng Shi, Shuang Jiang, Jiahui Sun, Gilwa Borjigin, Qi Li, Yuanqiu Mu, Chunjuan Yang, Zhenyue Wang, Haixue Kuang
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Molecules
Subjects:
UHPLC-ESI-MS/MS
<i>Picrorhiza scrophulariiflora</i>
iridoids
rat
pharmacokinetics
Online Access:https://www.mdpi.com/1420-3049/28/15/5925

Internet

https://www.mdpi.com/1420-3049/28/15/5925

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