Streamlining physiologically‐based pharmacokinetic model design for intravenous delivery of nanoparticle drugs

Abstract Physiologically‐based pharmacokinetic (PBPK) modeling for nanoparticles elucidates the nanoparticle drug’s disposition in the body and serves a vital role in drug development and clinical studies. This paper offers a systematic and tutorial‐like approach to developing a model structure and...

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Bibliographic Details
Main Authors: Anh‐Dung Le, Helen J. Wearing, Dingsheng Li
Format: Article
Language:English
Published: Wiley 2022-04-01
Series:CPT: Pharmacometrics & Systems Pharmacology
Online Access:https://doi.org/10.1002/psp4.12762