Ahi1 regulates serotonin production by the GR/ERβ/TPH2 pathway involving sexual differences in depressive behaviors

Abstract Background Depression is one of the most common psychiatric diseases. The monoamine transmitter theory suggests that neurotransmitters are involved in the mechanism of depression; however, the regulation on serotonin production is still unclear. We previously showed that Ahi1 knockout (KO)...

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Bibliographic Details
Main Authors: Bin Wang, Haixia Shi, Liyan Ren, Zhigang Miao, Bo Wan, Hao Yang, Xiaotang Fan, Jan-Ake Gustafsson, Miao Sun, Xingshun Xu
Format: Article
Language:English
Published: BMC 2022-05-01
Series:Cell Communication and Signaling
Subjects:
Online Access:https://doi.org/10.1186/s12964-022-00894-4